Can phenytoin cause anemia

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August undefined, 2024

WebAnemia in liver disease can be due to many causes. Macrocytic anemia could be due to lack of vitamin B12 or folic acid which could be due to nutritional causes. Low transferrin can be due to poor production of transferrin by the liver, due to liver disease or excessive loss of transferrin through the kidneys into the urine. WebApr 11, 2024 · The number of people living with chronic kidney disease (CKD) is growing as our global population continues to expand. With aging, diabetes, and cardiovascular disease being major harbingers of kidney disease, the number of people diagnosed with diabetic kidney disease (DKD) has grown concurrently. Poor clinical outcomes in DKD could be …

Dilantin Disease Interactions - Drugs.com

WebOct 22, 2015 · Phenytoin and other anticonvulsant agents have also been associated with the development of megaloblastic anemia. However, a … WebApr 13, 2024 · Megaloblastic anemia is caused by deficiency or impairment of utilization of vitamin B12 or folate. Nonmegaloblastic anemia may be the result of liver dysfunction, alcoholism, myelodysplastic syndrome (MDS), or hypothyroidism. Common causes of macrocytosis are different by region and setting. cto vs ato

Anticonvulsant-induced aplastic anemia: increased …

WebJan 4, 2024 · Symptoms. Initially, iron deficiency anemia can be so mild that it goes unnoticed. But as the body becomes more deficient in iron and anemia worsens, the signs and symptoms intensify. Iron deficiency anemia signs and symptoms may include: Extreme fatigue. Weakness. Pale skin. WebPhenytoin may cause swelling and bleeding of the gums. ... (including liver disease caused by past phenytoin use), lupus, folate or vitamin B-12 deficiency (megaloblastic anemia). ... WebNov 10, 2024 · Increasing evidence supports the use of rituximab in AIHA, particularly in warm antibody AIHA. [49, 50, 51] Although rituximab is increasingly used in steroid-refractory warm AIHA, [] results of a phase III trial in 64 patients support its use as first-line therapy for warm AIHA, in combination with corticosteroids.Birgens et al reported that … cto vs tech lead

Phenytoin (Oral Route) Side Effects - Mayo Clinic

WebApr 1, 2024 · Phenytoin may cause heart problems, including a slow heartbeat. Check with your doctor right away if you have chest pain, dizziness, or tiredness. This medicine may cause liver problems. Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellow ... WebMegaloblastic anaemia due to phenytoin sodium. Megaloblastic anaemia due to phenytoin sodium. Megaloblastic anaemia due to phenytoin sodium. Megaloblastic anaemia due … cto vs engineering managerWebMegaloblastic anemia is a type of macrocytic anemia.An anemia is a red blood cell defect that can lead to an undersupply of oxygen. Megaloblastic anemia results from inhibition of DNA synthesis during red blood cell … earthsea cycle mobi

"WebCauses of this type of anemia include: Too little folic acid in your diet; Hemolytic anemia; Long-term alcoholism; Use of certain medicines (such as phenytoin [Dilantin], methotrexate, sulfasalazine, triamterene, pyrimethamine, trimethoprim-sulfamethoxazole, and barbiturates) The following raise your risk for this type of anemia: Alcoholism " - Can phenytoin cause anemia

Can phenytoin cause anemia

Diagnosis and treatment of macrocytic anemias in adults

WebDrugs that can cause this type of hemolytic anemia include: Cephalosporins (a class of antibiotics), most common cause; Dapsone; Levodopa; Levofloxacin; Methyldopa; … WebThe antiepileptic drugs need to be checked for a dosage modulation, assessment of adverse effects due to chronic usage over years like megaloblastic anemia, gingival hypertrophu …

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WebFeb 12, 2024 · Dose reductions may also result in normalization of white blood cell counts. Aplastic anemia has been reported (although many of the reported cases had confounding exposures to other medications). The manufacturer reports an incidence of 2 per 1,000,000 patients for aplastic anemia and 6 per 1,000,000 patients for agranulocytosis. WebPhenytoin also can cause anemia. Because it interferes with vitamin D metabolism, phenytoin can cause weakening of the bones (osteomalacia). Other important side …

WebAntiepileptic drugs carbamazepine, phenytoin, and valproic acid induced aplastic anemia occurs via toxic metabolites. 11–13 The risk of aplastic anemia ranging from 1.4 to 60 cases/million, was detected among users of carbamazepine (within a 5-month period). 14 Felbamate proved to be a risk factor for aplastic anemia with an incidence of 127 ... WebFeb 11, 2024 · Causes of anemia. Different types of anemia have different causes. They include: Iron deficiency anemia. This most common type of anemia is caused by a …

WebApr 1, 2024 · This medicine may cause serious allergic reactions, including angioedema, which can be life-threatening and require immediate medical attention. Tell your doctor right away if you or your child have large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs after using this medicine. WebAntiepileptic drugs carbamazepine, phenytoin, and valproic acid induced aplastic anemia occurs via toxic metabolites. 11–13 The risk of aplastic anemia ranging from 1.4 to 60 cases/million, was detected among users of carbamazepine (within a 5-month period). 14 Felbamate proved to be a risk factor for aplastic anemia with an incidence of 127 ...

WebDiphenylhydantoin (Dilantin) has been used extensively as anticonvulsant therapy since its introduction in 1938, as has phenobarbital since 1912. It was not until 1952 that Mannheimer et al. 1 described leukopenia and megaloblastic anemia in an epileptic patient being treated with diphenylhydantoin.

WebNov 7, 2024 · These drugs are associated with a range of hematologic disorders ranging from mild thrombocytopenia or neutropenia to severe anemia, red cell aplasia, or bone … earthsea cycle box setWebA 53-yr-old man sequentially developed aplastic anemia from phenytoin and carbamazepine. Both compounds undergo metabolism to potentially toxic arene oxide … earthsea cycle booksWebPhenytoin, particularly in high dosages, may cause hyperglycemia by inhibiting insulin release. The drug may also raise serum glucose levels in diabetic patients. Therapy with phenytoin should be administered cautiously in patients with diabetes mellitus, glucose intolerance, or a predisposition to hyperglycemia. cto vulnerabilityWebAnemia can be caused by many conditions, including loss of blood during heavy menstruation, pregnancy, blood donation, bleeding ulcers, chronic heart failure, and surgery (before and after). There is also a type of anemia called anemia of chronic disease, which can occur in people with chronic kidney failure and those undergoing chemotherapy. earthsea book series reviewWebFeb 22, 2024 · Rarely, warfarin can cause the death of skin tissue (necrosis). This complication occurs within a few days of starting warfarin treatment. Seek immediate medical care if you notice sores, changes in skin color or temperature, or severe pain on your skin. Talk to your health care provider about these less serious side effects. earthsea cycle books in orderWebJul 11, 2024 · National Center for Biotechnology Information earthsea cycle seriesWebUse of certain medicines (such as phenytoin [Dilantin], methotrexate, sulfasalazine, triamterene, pyrimethamine, trimethoprim-sulfamethoxazole, and barbiturates) ... Symptoms of anemia can cause discomfort. In pregnant women, folate deficiency has been associated with neural tube or spinal defects (such as spina bifida) ... earthsea cycle reading order